Role of TESA in helping conception with azoospermia

4th March 2023

Azoospermia is a medical condition in which a man has no measurable amount of sperm in his semen. This condition affects about 1% of the male population and is a major cause of male infertility. Infertility can be a devastating experience for couples who are trying to conceive, and azoospermia can make it even more challenging.

However, there are several options available to couples trying to conceive despite azoospermia, including Testicular Sperm Extraction and Aspiration (TESA). TESA is a surgical procedure used to extract sperm directly from the testicles of men with azoospermia. In this article, we will discuss the role of TESA in helping conception with azoospermia.

What is TESA?

TESA is a minimally invasive surgical procedure that involves extracting sperm from the testicles. The procedure is usually done under local anesthesia, and it involves using a fine needle to aspirate fluid and tissue from the testicle. This fluid and tissue are then examined under a microscope to identify the presence of viable sperm.

TESA is typically performed on men who have azoospermia due to a blockage in the reproductive tract. This blockage prevents sperm from reaching the semen, and it can be caused by a variety of factors, including infection, injury, or surgery. In some cases, azoospermia may be caused by a failure of the testes to produce sperm, known as non-obstructive azoospermia.

How TESA Helps Conception with Azoospermia

TESA can be a helpful tool in helping couples achieve conception despite azoospermia. When sperm is extracted through TESA, it can be used for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In IVF, the sperm is mixed with the woman's eggs in a lab dish to allow fertilization to occur. In ICSI, a single sperm is injected directly into an egg to achieve fertilization.

In cases where there is non-obstructive azoospermia, TESA can also be used to retrieve immature sperm cells from the testicles. These cells can be cultured in a laboratory to mature and develop into fully functional sperm. This technique is known as testicular sperm extraction with intracytoplasmic sperm injection (TESE-ICSI).

TESA is also a viable option for men who have undergone a vasectomy but wish to have more children. In these cases, TESA can be used to extract sperm from the testicles, which can then be used for IVF or ICSI.


Azoospermia can be a challenging condition for couples trying to conceive, but TESA can provide a solution. By extracting sperm directly from the testicles, TESA can help couples achieve conception through IVF or ICSI. This technique is particularly useful in cases where azoospermia is caused by a blockage in the reproductive tract or when men have undergone a vasectomy. TESA is a minimally invasive surgical procedure that is usually performed on an outpatient basis, and it can significantly increase the chances of conception for couples struggling with azoospermia. We, at Genome The Fertility Centre provide you a wide range of treatment related to pregnancy and infertility. With a team of highly experienced Reproductive Medicine Specialists, full time embryologists and advanced technology, we offer medical procedures like TESA, IVF/ICSI to help you enjoy the much coveted parenthood.


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